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However, treatment with the fully human monoclonal IFN- antibody EI-001 (experimental code 2A6Q) at a concentration of 10 g/ml alleviates the inhibitory effect of IFN- on melanocyte viability, increases melanin production, reverses IFN--induced ROS accumulation and ferroptosis, and significantly reduces melanocyte apoptosis as detected by flow cytometry

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Inflammation is also thought to be a key player in the cardiac conduction system malfunction seen in FD (56)